Cargando…
Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis
A 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415123/ https://www.ncbi.nlm.nih.gov/pubmed/32802546 http://dx.doi.org/10.1155/2020/3079869 |
_version_ | 1783569106027413504 |
---|---|
author | Alhazmi, Ahmed Cheikh, Mohamed Moulaye Hassan, Rola Yousef |
author_facet | Alhazmi, Ahmed Cheikh, Mohamed Moulaye Hassan, Rola Yousef |
author_sort | Alhazmi, Ahmed |
collection | PubMed |
description | A 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for alveolar hemorrhage and a rarely reported pneumomediastinum. Along with this constellation of findings, a positive antiproteinase 3 helped to confirm this patient's diagnosis of granulomatosis with polyangiitis. Treatment commenced with sessions of plasma exchange and pulse steroids along with cyclophosphamide infusions. The patient had since improved and made a full recovery. This case report highlights the rarely described pneumomediastinum in association with vasculitides. |
format | Online Article Text |
id | pubmed-7415123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-74151232020-08-14 Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis Alhazmi, Ahmed Cheikh, Mohamed Moulaye Hassan, Rola Yousef Case Rep Rheumatol Case Report A 38-year-old hypertensive male with a smoking history presented to the emergency room with significant hemoptysis, arthritis, and a purpuric rash. Other findings included a dropping hemoglobin and acute kidney injury with microscopic hematuria. The pulmonary computed tomography was significant for alveolar hemorrhage and a rarely reported pneumomediastinum. Along with this constellation of findings, a positive antiproteinase 3 helped to confirm this patient's diagnosis of granulomatosis with polyangiitis. Treatment commenced with sessions of plasma exchange and pulse steroids along with cyclophosphamide infusions. The patient had since improved and made a full recovery. This case report highlights the rarely described pneumomediastinum in association with vasculitides. Hindawi 2020-07-30 /pmc/articles/PMC7415123/ /pubmed/32802546 http://dx.doi.org/10.1155/2020/3079869 Text en Copyright © 2020 Ahmed Alhazmi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Alhazmi, Ahmed Cheikh, Mohamed Moulaye Hassan, Rola Yousef Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title | Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title_full | Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title_fullStr | Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title_full_unstemmed | Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title_short | Pneumomediastinum as a Manifestation of Granulomatosis with Polyangiitis |
title_sort | pneumomediastinum as a manifestation of granulomatosis with polyangiitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415123/ https://www.ncbi.nlm.nih.gov/pubmed/32802546 http://dx.doi.org/10.1155/2020/3079869 |
work_keys_str_mv | AT alhazmiahmed pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis AT cheikhmohamedmoulaye pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis AT hassanrolayousef pneumomediastinumasamanifestationofgranulomatosiswithpolyangiitis |