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Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion

Subcellular dynamics of non-muscle myosin 2 (NM2) is crucial for a broad-array of cellular functions. To unveil mechanisms of NM2 pharmacological control, we determined how the dynamics of NM2 diffusion is affected by NM2′s allosteric inhibitors, i.e. blebbistatin derivatives, as compared to Y-27632...

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Detalles Bibliográficos
Autores principales:	Horváth, Ádám I., Gyimesi, Máté, Várkuti, Boglárka H., Képiró, Miklós, Szegvári, Gábor, Lőrincz, István, Hegyi, György, Kovács, Mihály, Málnási-Csizmadia, András
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415145/ https://www.ncbi.nlm.nih.gov/pubmed/32769996 http://dx.doi.org/10.1038/s41598-020-69853-8

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