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VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway

INTRODUCTION: To investigate the protective effect of VX‐765 on human umbilical mesenchymal stem cells (HUMSCs) in stroke and its mechanism. MATERIALS AND METHODS: Mouse models of ischemic stroke were established using the distal middle cerebral artery occlusion (dMCAO) method. The dMCAO mice were a...

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Detalles Bibliográficos
Autores principales:	Sun, Zhezhe, Gu, Lei, Wu, Ke, Wang, Kankai, Ru, Junnan, Yang, Su, Wang, Zhenzhong, Zhuge, Qichuan, Huang, Lijie, Huang, Shengwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415204/ https://www.ncbi.nlm.nih.gov/pubmed/32459063 http://dx.doi.org/10.1111/cns.13400

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