Caspase‐1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia

AIMS: The involvement of pyroptosis in ischemic stroke remains to be established. Therefore, we used the specific pyroptosis inhibitor Vx765 as an experimental intervention target in a murine model of stroke. METHODS: A total of 564 C57BL/6 mice were subjected to photothrombotic procedures and treat...

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Detalles Bibliográficos
Autores principales: Li, Jia, Hao, Jia‐Huan, Yao, Di, Li, Rong, Li, Xue‐Fei, Yu, Zhi‐Yuan, Luo, Xiang, Liu, Xing‐Hua, Wang, Ming‐Huan, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415206/
https://www.ncbi.nlm.nih.gov/pubmed/32343048
http://dx.doi.org/10.1111/cns.13384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415206/
https://www.ncbi.nlm.nih.gov/pubmed/32343048
http://dx.doi.org/10.1111/cns.13384

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