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Elimination of a Retinal Riboflavin Binding Protein Exacerbates Degeneration in a Model of Cone-Rod Dystrophy
PURPOSE: Riboflavin and its cofactors are essential for cellular energy generation, responses to oxidative stress, and overall homeostasis. Retbindin is a novel retina-specific riboflavin binding protein essential for the maintenance of retinal flavin levels, but its function remains poorly understo...
Autores principales: | Genc, Ayse M., Makia, Mustafa S., Sinha, Tirthankar, Conley, Shannon M., Al-Ubaidi, Muayyad R., Naash, Muna I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415289/ https://www.ncbi.nlm.nih.gov/pubmed/32516403 http://dx.doi.org/10.1167/iovs.61.6.17 |
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