Investigation of Binding Affinity between Potential Antiviral Agents and PB2 Protein of Influenza A: Non-equilibrium Molecular Dynamics Simulation Approach

The PB2 protein of the influenza virus RNA polymerase is a major virulence determinant of influenza viruses. It binds to the cap structure at the 5' end of host mRNA to generate short capped RNA fragments that are used as primers for viral transcription named cap-snatching. A large number of th...

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Detalles Bibliográficos
Autores principales: Pham, Tri, Nguyen, Hoang Linh, Phan-Toai, Tuyn, Nguyen, Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415388/
https://www.ncbi.nlm.nih.gov/pubmed/32788882
http://dx.doi.org/10.7150/ijms.46231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415388/
https://www.ncbi.nlm.nih.gov/pubmed/32788882
http://dx.doi.org/10.7150/ijms.46231

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