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Highly bioavailable Berberine formulation improves Glucocorticoid Receptor-mediated Insulin Resistance via reduction in association of the Glucocorticoid Receptor with phosphatidylinositol-3-kinase

Excess glucocorticoid (GC) production is known to induce obesity and insulin resistance through increased activation of the glucocorticoid receptor (GR). The molecular mechanism for the non-genomic effects of excessive circulating GC on the insulin-signalling pathway in skeletal muscle is unknown. T...

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Detalles Bibliográficos
Autores principales: Meng, Zhaojie, Yu, Yang, Zhang, Yining, Yang, Xuehan, Lv, Xiaoyan, Guan, Fengying, Hatch, Grant M., Zhang, Ming, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415432/
https://www.ncbi.nlm.nih.gov/pubmed/32792855
http://dx.doi.org/10.7150/ijbs.39508