Cargando…

AURKB Promotes the Metastasis of Gastric Cancer, Possibly by Inducing EMT

AIM: To investigate the function of Aurora kinase B (AURKB) in gastric cancer (GC). METHODS: Immunohistochemistry was used to assay the expression of AURKB in 50 pairs of GC and adjacent tissues, and qRT-PCR was conducted to test AURKB expression in normal gastric epithelial and GC cell lines. Two s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhen, Yu, Zhu, Wang, Gong-he, Zhou, Yi-ming, Deng, Jian-ping, Feng, Yue, Chen, Jun-qiang, Tian, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415439/ https://www.ncbi.nlm.nih.gov/pubmed/32801915 http://dx.doi.org/10.2147/CMAR.S254250

Ejemplares similares

AURKB activates EMT through PI3K/AKT signaling axis to promote ICC progression
por: Ma, Peng, et al.
Publicado: (2023)

AURKB promotes gastric cancer progression via activation of CCND1 expression
por: Nie, Min, et al.
Publicado: (2020)

ALKBH5 promotes the proliferation of renal cell carcinoma by regulating AURKB expression in an m(6)A-dependent manner
por: Zhang, Xiaolei, et al.
Publicado: (2020)

AURKB as a Promising Prognostic Biomarker in Hepatocellular Carcinoma
por: Xiao, Jingchuan, et al.
Publicado: (2021)

AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma
por: Wang, Huixue, et al.
Publicado: (2023)

AURKB: a promising biomarker in clear cell renal cell carcinoma
por: Wan, Bangbei, et al.
Publicado: (2019)

Gigantol Attenuates the Metastasis of Human Bladder Cancer Cells, Possibly Through Wnt/EMT Signaling
por: Zhao, Meili, et al.
Publicado: (2020)

CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer
por: Xu, Zhijun, et al.
Publicado: (2020)

Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer
por: Li, Wei, et al.
Publicado: (2019)

SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer
por: Bao, Zhen, et al.
Publicado: (2022)

Haspin inhibition reveals functional differences of interchromatid axis–localized AURKB and AURKC
por: Quartuccio, Suzanne M., et al.
Publicado: (2017)

MYC degradation via AURKB inhibition: a new brake in the path to T-ALL
por: Zhang, Wu, et al.
Publicado: (2020)

Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT
por: Hu, Qingjiang, et al.
Publicado: (2020)

GDF15 promotes EMT and metastasis in colorectal cancer
por: Li, Chen, et al.
Publicado: (2015)

SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway
por: Tian, Shan, et al.
Publicado: (2020)

Chemokine/GPCR Signaling-Mediated EMT in Cancer Metastasis
por: Tian, Xutengyue, et al.
Publicado: (2022)

Issues on peritoneal metastasis of gastric cancer: an update
por: Wang, Zhen, et al.
Publicado: (2019)

AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer
por: Xu, Fen, et al.
Publicado: (2020)

Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress
por: Lin, Xian-Ming, et al.
Publicado: (2021)

Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway
por: Yuan, Wanqiong, et al.
Publicado: (2016)

Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer
por: Cao, Qing-Hua, et al.
Publicado: (2018)

HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E
por: Chang, Xiaoyu, et al.
Publicado: (2020)

The DeltaN p63 Promotes EMT and Metastasis in Bladder Cancer by the PTEN/AKT Signalling Pathway
por: Tian, Yong-Hua, et al.
Publicado: (2022)

Galectin-1 Promotes Vasculogenic Mimicry in Gastric Cancer by Upregulating EMT Signaling
por: You, Xiaolan, et al.
Publicado: (2019)

AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome
por: Hall, Lisa L., et al.
Publicado: (2009)

Multi-omics analysis identifies potential mechanisms of AURKB in mediating poor outcome of lung adenocarcinoma
por: Huang, Jie, et al.
Publicado: (2021)

AURKB, in concert with REST, acts as an oxygen-sensitive epigenetic regulator of the hypoxic induction of MDM2
por: Kim, Iljin, et al.
Publicado: (2022)

Amplifications of AURKA and AURKB in a Burkitt lymphoma immunodeficiency-associated type: a case report
por: de Oliveira, Fábio Morato, et al.
Publicado: (2023)

EMT and tumor metastasis
por: Heerboth, Sarah, et al.
Publicado: (2015)

Potential Molecular Mechanisms of AURKB in the Oncogenesis and Progression of Osteosarcoma Cells: A Label-Free Quantitative Proteomics Analysis
por: Pi, Wen-Sen, et al.
Publicado: (2019)

G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner
por: Hu, Lei, et al.
Publicado: (2018)

NEK4 kinase regulates EMT to promote lung cancer metastasis
por: Ding, Nian‐Hua, et al.
Publicado: (2018)

SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis
por: Zhang, Xu, et al.
Publicado: (2018)

Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT
por: He, Zhen-Yu, et al.
Publicado: (2016)

AB17. ADT treatment promotes PCa EMT and metastasis
por: Niu, Yuan-Jie
Publicado: (2014)

DSTYK Promotes Metastasis and Chemoresistance via EMT in Colorectal Cancer
por: Zhang, Jinyu, et al.
Publicado: (2020)

Mitotic Arrest-Deficient Protein 2B Overexpressed in Lung Cancer Promotes Proliferation, EMT, and Metastasis
por: Zhang, Hua, et al.
Publicado: (2019)

AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy
por: Bertran-Alamillo, Jordi, et al.
Publicado: (2019)

Expression and clinical significance of AURKB gene in lung adenocarcinoma: Analysis based on the data-mining of bioinformatic database
por: Gao, Xiaoyan, et al.
Publicado: (2021)

lncRNA ELFN1-AS1 enhances the progression of colon cancer by targeting miR-4270 to upregulate AURKB
por: Peng, Shuangqin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hhh6pir2l0st29qtes72oi83f5