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Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages

BACKGROUND: Dioxygenase 12-lipoxygenase (12-LOX) plays an important role in tumorigenesis and promotes angiogenesis and proliferation in several tumors, including prostate and breast tumors. Radiotherapy enhances the expression of 12-LOX in esophageal squamous cell carcinoma (ESCC). Two types of mac...

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Detalles Bibliográficos
Autores principales: Mi, Si, Qu, Yan, Chen, Xue, Wen, Zhihua, Chen, Pengxiang, Cheng, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415441/
https://www.ncbi.nlm.nih.gov/pubmed/32801779
http://dx.doi.org/10.2147/OTT.S257852