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An analysis of the effect of mu-opioid receptor gene (OPRM1) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence

This study explored the effect of OPRM1 promoter region DNA methylation on the outcome of treatment with the opioid antagonist naltrexone (NTX) for alcohol dependence (AD). Ninety-three patients with DSM-IV AD [41 African Americans (AAs) and 52 European Americans (EAs)] received double-blind treatme...

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Detalles Bibliográficos
Autores principales: Lin, Yufei, Kranzler, Henry R., Farrer, Lindsay A., Xu, Hongqin, Henderson, David C., Zhang, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415483/
https://www.ncbi.nlm.nih.gov/pubmed/32029903
http://dx.doi.org/10.1038/s41397-020-0158-1