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Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells

In vitro assessment of genotoxicity as an early warning tool for carcinogenicity mainly relies on recording cytogenetic damages (micronuclei, nucleoplasmic bridges) in tumour-derived mammalian cell lines like V79 or CHO. The forecasting power of the corresponding standardised test is based on epidem...

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Detalles Bibliográficos
Autores principales:	Hölzel, Bastian Niklas, Pfannkuche, Kurt, Allner, Bernhard, Allner, Hans Thomas, Hescheler, Jürgen, Derichsweiler, Daniel, Hollert, Henner, Schiwy, Andreas, Brendt, Julia, Schaffeld, Michael, Froschauer, Alexander, Stahlschmidt-Allner, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Genotoxicity and Carcinogenicity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415759/ https://www.ncbi.nlm.nih.gov/pubmed/32700163 http://dx.doi.org/10.1007/s00204-020-02821-3

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