Metabolic rewiring of synthetic pyruvate dehydrogenase bypasses for acetone production in cyanobacteria

Designing synthetic pathways for efficient CO(2) fixation and conversion is essential for sustainable chemical production. Here we have designed a synthetic acetate‐acetyl‐CoA/malonyl‐CoA (AAM) bypass to overcome an enzymatic activity of pyruvate dehydrogenase complex. This synthetic pathway utilize...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jeong, Son, Jigyeong, Sim, Sang Jun, Woo, Han Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415776/
https://www.ncbi.nlm.nih.gov/pubmed/31960579
http://dx.doi.org/10.1111/pbi.13342

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