Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway

Mesenchymal stem cells (MSCs) have emerged as ideal cell-based therapeutic candidates for the structural and functional restoration of the diseased kidney. Glial cell line-derived neurotrophic factor (GDNF) has been demonstrated to promote the therapeutic effect of MSCs on ameliorating renal injury....

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Detalles Bibliográficos
Autores principales: Chen, Lu, Wang, Yanping, Li, Shulin, Zuo, Bangjie, Zhang, Xiangyu, Wang, Fengzhen, Sun, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415791/
https://www.ncbi.nlm.nih.gov/pubmed/32802201
http://dx.doi.org/10.7150/thno.43315

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