Cargando…

TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

Background and Aim: Increasing evidence suggests that spinal cord injury (SCI)-induced defects in autophagic flux may contribute to an impaired ability for neurological repair following injury. Transcription factor E3 (TFE3) plays a crucial role in oxidative metabolism, lysosomal homeostasis, and au...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Kailiang, Zheng, Zhilong, Li, Yao, Han, Wen, Zhang, Jing, Mao, Yuqin, Chen, Huanwen, Zhang, Wanying, Liu, Mi, Xie, Ling, Zhang, Hongyu, Xu, Huazi, Xiao, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415792/ https://www.ncbi.nlm.nih.gov/pubmed/32802192 http://dx.doi.org/10.7150/thno.46566

Ejemplares similares

Trehalose Augments Neuron Survival and Improves Recovery from Spinal Cord Injury via mTOR-Independent Activation of Autophagy
por: Zhou, Kailiang, et al.
Publicado: (2021)

The Temporal Pattern, Flux, and Function of Autophagy in Spinal Cord Injury
por: Zhou, Kailiang, et al.
Publicado: (2017)

GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation
por: Xu, Yu, et al.
Publicado: (2021)

Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
por: Wu, Chenyu, et al.
Publicado: (2021)

Role of Pyroptosis in Traumatic Brain and Spinal Cord Injuries
por: Hu, Xinli, et al.
Publicado: (2020)

Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule
por: Wang, Haoli, et al.
Publicado: (2020)

3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
por: Zhang, Haojie, et al.
Publicado: (2023)

Kruppel-like factor 2 contributes to blood-spinal cord barrier integrity and functional recovery from spinal cord injury by augmenting autophagic flux
por: He, Zili, et al.
Publicado: (2023)

FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival
por: Zhou, Kailiang, et al.
Publicado: (2019)

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury
por: Zhou, Yulong, et al.
Publicado: (2016)

Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury
por: Zhou, Yulong, et al.
Publicado: (2016)

Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement
por: Wu, Chenyu, et al.
Publicado: (2020)

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement
por: Wu, Hongqiang, et al.
Publicado: (2019)

Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development
por: Tang, Qian, et al.
Publicado: (2017)

Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination
por: Li, Jiafeng, et al.
Publicado: (2021)

TFE3 Alleviates Hepatic Steatosis through Autophagy-Induced Lipophagy and PGC1α-Mediated Fatty Acid β-Oxidation
por: Xiong, Jie, et al.
Publicado: (2016)

Cyclic helix B peptide alleviates proinflammatory cell death and improves functional recovery after traumatic spinal cord injury
por: Xu, Yu, et al.
Publicado: (2023)

TFE3-Mediated Autophagy is Involved in Dopaminergic Neurodegeneration in Parkinson’s Disease
por: He, Xin, et al.
Publicado: (2021)

Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress
por: Zhang, Jing, et al.
Publicado: (2021)

Case Report: Gastrointestinal PEComa With TFE3 Rearrangement Treated With Anti-VEGFR TKI Apatinib
por: Xu, Jiaming, et al.
Publicado: (2020)

Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis
por: Chen, Xian-Bing, et al.
Publicado: (2018)

Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3
por: Dang, Thao Thi, et al.
Publicado: (2021)

Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord
por: Duarte-Silva, Eduardo, et al.
Publicado: (2021)

Dl-3-n-butylphthalide prevents the disruption of blood-spinal cord barrier via inhibiting endoplasmic reticulum stress following spinal cord injury
por: Zheng, Binbin, et al.
Publicado: (2017)

MiT/TFE factors control ER‐phagy via transcriptional regulation of FAM134B
por: Cinque, Laura, et al.
Publicado: (2020)

Taurine Alleviates Cadmium-Induced Hepatotoxicity by Regulating Autophagy Flux
por: Duan, Yuntian, et al.
Publicado: (2023)

Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death
por: Liu, S, et al.
Publicado: (2015)

Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation
por: Zheng, Gang, et al.
Publicado: (2019)

The repair and autophagy mechanisms of hypoxia‐regulated bFGF‐modified primary embryonic neural stem cells in spinal cord injury
por: Zhu, Sipin, et al.
Publicado: (2020)

Epidermal growth factor attenuates blood‐spinal cord barrier disruption via PI3K/Akt/Rac1 pathway after acute spinal cord injury
por: Zheng, Binbin, et al.
Publicado: (2016)

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
por: Annunziata, Ida, et al.
Publicado: (2019)

Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization
por: Zhang, Haojie, et al.
Publicado: (2023)

Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model
por: Liu, Yongda, et al.
Publicado: (2020)

CARM1 promotes gastric cancer progression by regulating TFE3 mediated autophagy enhancement through the cytoplasmic AMPK-mTOR and nuclear AMPK-CARM1-TFE3 signaling pathways
por: Yang, Suzhen, et al.
Publicado: (2022)

Caloric Restriction Alleviates CFA-Induced Inflammatory Pain via Elevating β-Hydroxybutyric Acid Expression and Restoring Autophagic Flux in the Spinal Cord
por: Liu, Chang, et al.
Publicado: (2022)

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
por: Chen, Guo, et al.
Publicado: (2019)

Jia-Ji Electro-Acupuncture Improves Locomotor Function With Spinal Cord Injury by Regulation of Autophagy Flux and Inhibition of Necroptosis
por: Hongna, Yin, et al.
Publicado: (2021)

NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy
por: Fan, Tengfei, et al.
Publicado: (2022)

Review of Epidural Spinal Cord Stimulation for Augmenting Cough after Spinal Cord Injury
por: Hachmann, Jan T., et al.
Publicado: (2017)

FGF21 alleviates microvascular damage following limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and anti-oxidative response
por: Chen, Fanfeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j1u9ov9qq73jb9e1nii2e3sr1p