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USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer

Background: Tumor associated macrophages (TAMs) have strong plasticity and if reprogrammed, can clear tumor cells and regulate the adaptive immune system for cancer immunotherapy. Deubiquitinating enzymes (DUBs), which can remove ubiquitin (Ub) from Ub-modified substrates, have been associated with...

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Detalles Bibliográficos
Autores principales: Dai, Xiaomeng, Lu, Lisen, Deng, Suke, Meng, Jingshu, Wan, Chao, Huang, Jing, Sun, Yajie, Hu, Yan, Wu, Bian, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415808/
https://www.ncbi.nlm.nih.gov/pubmed/32802195
http://dx.doi.org/10.7150/thno.47137