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USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer
Background: Tumor associated macrophages (TAMs) have strong plasticity and if reprogrammed, can clear tumor cells and regulate the adaptive immune system for cancer immunotherapy. Deubiquitinating enzymes (DUBs), which can remove ubiquitin (Ub) from Ub-modified substrates, have been associated with...
Autores principales: | Dai, Xiaomeng, Lu, Lisen, Deng, Suke, Meng, Jingshu, Wan, Chao, Huang, Jing, Sun, Yajie, Hu, Yan, Wu, Bian, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415808/ https://www.ncbi.nlm.nih.gov/pubmed/32802195 http://dx.doi.org/10.7150/thno.47137 |
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