Technical Considerations for Use of Oligonucleotide Solution API

The most common approach for the manufacture of oligonucleotides includes isolation of the active pharmaceutical ingredient (API) via lyophilization to provide a solid product, which is then dissolved to provide an aqueous formulation. It is well known from the development and manufacture of large m...

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Detalles Bibliográficos
Autores principales: Muslehiddinoglu, Jale, Simler, Robert, Hill, Malcolm L., Mueller, Claudia, Amery, John H. A., Dixon, Leigh, Watson, Anna, Storch, Kirsten, Gazziola, Cinzia, Gielen, Frank, Lange, Stefan Andreas, Prail, Jeremy D., Nesta, Doug P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Issues in Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415879/
https://www.ncbi.nlm.nih.gov/pubmed/32379529
http://dx.doi.org/10.1089/nat.2020.0846

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