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Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments
Recent in situ multiplexed profiling techniques provide insight into microenvironment formation, maintenance, and transformation through a lens of localized cellular phenotype distribution. In this article, we introduce a method for recovering signatures of microenvironments from such data. We use t...
Autores principales: | Chen, Zhenghao, Soifer, Ilya, Hilton, Hugo, Keren, Leeat, Jojic, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415889/ https://www.ncbi.nlm.nih.gov/pubmed/32243203 http://dx.doi.org/10.1089/cmb.2019.0340 |
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