All-trans-Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

PURPOSE: Extracellular accumulation of all-trans-retinaldehyde (atRAL), a highly reactive visual cycle intermediate, is toxic to cells of the outer retina and contributes to retinal and macular degenerations. However, the contribution of atRAL to retinal capillary function has not been studied. We h...

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Detalles Bibliográficos
Autores principales: Dreffs, Alyssa, Lin, Cheng-Mao, Liu, Xuwen, Shanmugam, Sumathi, Abcouwer, Steven F., Kern, Timothy S., Antonetti, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415894/
https://www.ncbi.nlm.nih.gov/pubmed/32492112
http://dx.doi.org/10.1167/iovs.61.6.8

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