Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1α Signaling in Retinal Glial Cells under Hypoxic Conditions

PURPOSE: Acrolein, a highly reactive unsaturated aldehyde, is known to facilitate glial cell migration, one of the pathological hallmarks in diabetic retinopathy. However, cellular mechanisms of acrolein generation in retinal glial cells remains elusive. In the present study, we investigated the rol...

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Detalles Bibliográficos
Autores principales: Wu, Di, Noda, Kousuke, Murata, Miyuki, Liu, Ye, Kanda, Atsuhiro, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415903/
https://www.ncbi.nlm.nih.gov/pubmed/32579679
http://dx.doi.org/10.1167/iovs.61.6.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415903/
https://www.ncbi.nlm.nih.gov/pubmed/32579679
http://dx.doi.org/10.1167/iovs.61.6.52

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