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Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice
Astrocytes play a key role in the progression of amyotrophic lateral sclerosis (ALS) by actively inducing the degeneration of motor neurons. Motor neurons isolated from receptor for advanced glycation end products (RAGE)‐knockout mice are resistant to the neurotoxic signal derived from ALS‐astrocyte...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415959/ https://www.ncbi.nlm.nih.gov/pubmed/32776498 http://dx.doi.org/10.1002/prp2.636 |