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Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice

Astrocytes play a key role in the progression of amyotrophic lateral sclerosis (ALS) by actively inducing the degeneration of motor neurons. Motor neurons isolated from receptor for advanced glycation end products (RAGE)‐knockout mice are resistant to the neurotoxic signal derived from ALS‐astrocyte...

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Detalles Bibliográficos
Autores principales:	Liu, Liping, Killoy, Kelby M., Vargas, Marcelo R., Yamamoto, Yasuhiko, Pehar, Mariana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Invited Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415959/ https://www.ncbi.nlm.nih.gov/pubmed/32776498 http://dx.doi.org/10.1002/prp2.636

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