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Engineered anti-inflammatory peptides inspired by mapping an evasin–chemokine interaction
Chemokines mediate leukocyte migration and homeostasis and are key targets in inflammatory diseases including atherosclerosis, cytokine storm, and chronic autoimmune disease. Chemokine redundancy and ensuing network robustness has frustrated therapeutic development. Salivary evasins from ticks bind...
Autores principales: | Darlot, Benoit, Eaton, James R. O., Geis-Asteggiante, Lucia, Yakala, Gopala K., Karuppanan, Kalimuthu, Davies, Graham, Robinson, Carol V., Kawamura, Akane, Bhattacharya, Shoumo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415964/ https://www.ncbi.nlm.nih.gov/pubmed/32471866 http://dx.doi.org/10.1074/jbc.RA120.014103 |
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