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Engineered anti-inflammatory peptides inspired by mapping an evasin–chemokine interaction

Chemokines mediate leukocyte migration and homeostasis and are key targets in inflammatory diseases including atherosclerosis, cytokine storm, and chronic autoimmune disease. Chemokine redundancy and ensuing network robustness has frustrated therapeutic development. Salivary evasins from ticks bind...

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Detalles Bibliográficos
Autores principales: Darlot, Benoit, Eaton, James R. O., Geis-Asteggiante, Lucia, Yakala, Gopala K., Karuppanan, Kalimuthu, Davies, Graham, Robinson, Carol V., Kawamura, Akane, Bhattacharya, Shoumo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415964/
https://www.ncbi.nlm.nih.gov/pubmed/32471866
http://dx.doi.org/10.1074/jbc.RA120.014103

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