Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

Numerous broadly neutralizing antibodies (bnAbs) have been identified that target the glycans of the HIV-1 envelope spike. Neutralization breadth is notable given that glycan processing can be substantially influenced by the presence or absence of neighboring glycans. Here, using a stabilized recomb...

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Detalles Bibliográficos
Autores principales: Seabright, Gemma E., Cottrell, Christopher A., van Gils, Marit J., D'addabbo, Alessio, Harvey, David J., Behrens, Anna-Janina, Allen, Joel D., Watanabe, Yasunori, Scaringi, Nicole, Polveroni, Thomas M., Maker, Allison, Vasiljevic, Snezana, de Val, Natalia, Sanders, Rogier W., Ward, Andrew B., Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416112/
https://www.ncbi.nlm.nih.gov/pubmed/32433992
http://dx.doi.org/10.1016/j.str.2020.04.022

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