Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex

Thiol-containing natural products possess a wide range of bioactivities. The burst of synthetic biology technology facilitates the discovery of new thiol-containing active ingredients. Herein, we report a sensitive, quick, and robust surface-enhanced Raman scattering technology for specific and mult...

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Detalles Bibliográficos
Autores principales: Hong, Yan, Wang, Rui, Jiang, Zhuoran, Cong, Zisong, Song, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416272/
https://www.ncbi.nlm.nih.gov/pubmed/32802063
http://dx.doi.org/10.1155/2020/9271236
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author Hong, Yan
Wang, Rui
Jiang, Zhuoran
Cong, Zisong
Song, Heng
author_facet Hong, Yan
Wang, Rui
Jiang, Zhuoran
Cong, Zisong
Song, Heng
author_sort Hong, Yan
collection PubMed
description Thiol-containing natural products possess a wide range of bioactivities. The burst of synthetic biology technology facilitates the discovery of new thiol-containing active ingredients. Herein, we report a sensitive, quick, and robust surface-enhanced Raman scattering technology for specific and multiplex detection of thiol-containing compounds without purification requirements and also indicating the thiols with different chemical environments. Using this platform, we successfully demonstrated the simultaneous detection of thiol-containing compounds from as low as 1 μM of analytes spiked in complex culture matrices.
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spelling pubmed-74162722020-08-14 Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex Hong, Yan Wang, Rui Jiang, Zhuoran Cong, Zisong Song, Heng Int J Anal Chem Research Article Thiol-containing natural products possess a wide range of bioactivities. The burst of synthetic biology technology facilitates the discovery of new thiol-containing active ingredients. Herein, we report a sensitive, quick, and robust surface-enhanced Raman scattering technology for specific and multiplex detection of thiol-containing compounds without purification requirements and also indicating the thiols with different chemical environments. Using this platform, we successfully demonstrated the simultaneous detection of thiol-containing compounds from as low as 1 μM of analytes spiked in complex culture matrices. Hindawi 2020-08-01 /pmc/articles/PMC7416272/ /pubmed/32802063 http://dx.doi.org/10.1155/2020/9271236 Text en Copyright © 2020 Yan Hong et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hong, Yan
Wang, Rui
Jiang, Zhuoran
Cong, Zisong
Song, Heng
Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title_full Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title_fullStr Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title_full_unstemmed Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title_short Rapid SERS Detection of Thiol-Containing Natural Products in Culturing Complex
title_sort rapid sers detection of thiol-containing natural products in culturing complex
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416272/
https://www.ncbi.nlm.nih.gov/pubmed/32802063
http://dx.doi.org/10.1155/2020/9271236
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