Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: a phenotypic and phylogenetic analysis

BACKGROUND: Bedaquiline and clofazimine are important drugs in the treatment of drug-resistant tuberculosis and are commonly used across southern Africa, although drug susceptibility testing is not routinely performed. In this study, we did a genotypic and phenotypic analysis of drug-resistant Mycob...

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Detalles Bibliográficos
Autores principales: Nimmo, Camus, Millard, James, van Dorp, Lucy, Brien, Kayleen, Moodley, Sashen, Wolf, Allison, Grant, Alison D, Padayatchi, Nesri, Pym, Alexander S, Balloux, François, O'Donnell, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416634/
https://www.ncbi.nlm.nih.gov/pubmed/32803174
http://dx.doi.org/10.1016/S2666-5247(20)30031-8

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