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Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines

OBJECTIVE: To estimate the prevalence of use of drugs to treat gastrointestinal disorders, according to demographic, socioeconomic, and health characteristics of the Brazilian population. METHODS: This is a population-based survey that interviewed individuals residing in cities of the five regions i...

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Autores principales: Pereira, Lucas Borges, Gonçalves, Ana Maria Rosa Freato, Fernandes, Camila Stéfani Estancial, Fontanella, Andréia Turmina, Francisco, Priscila Maria Stolses Bergamo, Mengue, Sotero Serrate, Borges, Rogério Boff, Pizzol, Tatiane da Silva Dal, Costa, Karen Sarmento
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416649/
https://www.ncbi.nlm.nih.gov/pubmed/32785451
http://dx.doi.org/10.31744/einstein_journal/2020AO5314
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author Pereira, Lucas Borges
Gonçalves, Ana Maria Rosa Freato
Fernandes, Camila Stéfani Estancial
Fontanella, Andréia Turmina
Francisco, Priscila Maria Stolses Bergamo
Mengue, Sotero Serrate
Borges, Rogério Boff
Pizzol, Tatiane da Silva Dal
Costa, Karen Sarmento
author_facet Pereira, Lucas Borges
Gonçalves, Ana Maria Rosa Freato
Fernandes, Camila Stéfani Estancial
Fontanella, Andréia Turmina
Francisco, Priscila Maria Stolses Bergamo
Mengue, Sotero Serrate
Borges, Rogério Boff
Pizzol, Tatiane da Silva Dal
Costa, Karen Sarmento
author_sort Pereira, Lucas Borges
collection PubMed
description OBJECTIVE: To estimate the prevalence of use of drugs to treat gastrointestinal disorders, according to demographic, socioeconomic, and health characteristics of the Brazilian population. METHODS: This is a population-based survey that interviewed individuals residing in cities of the five regions in Brazil. The study sample was composed of 32,348 individuals aged 20 or more years. The profile of use of drugs for gastrointestinal disorders was evaluated considering the variables sex, age, healthcare plan, region, and number of chronic diseases. We also analyzed the frequency of individuals who declared using other drugs, besides those already employed for treatment of gastrointestinal disorders. Additionally, the estimated frequencies of the drug classes used were determined. RESULTS: The prevalence of use of drugs for gastrointestinal disorders in Brazil was 6.9% (95% confidence interval − 6.4-7.6), higher in females, among persons aged over 60 years, in those who had a private healthcare insurance, and presented with two or more chronic diseases. It was noted that 42.9% of the aged who used drugs for gastrointestinal disorders were also on polypharmacy. As to the classes of drugs, 82% corresponded to drugs for the food tract and metabolism, particularly proton pumps inhibitors. CONCLUSION: The use of drugs for treatment of gastrointestinal disorders was significant among women and elderly. In this age group, consumption may be linked to gastric protection due to polypharmacy. This study is an unprecedented opportunity to observe the self-reported consumption profile of these drugs in Brazil and, therefore, could subsidize strategies to promote their rational use.
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spelling pubmed-74166492020-08-19 Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines Pereira, Lucas Borges Gonçalves, Ana Maria Rosa Freato Fernandes, Camila Stéfani Estancial Fontanella, Andréia Turmina Francisco, Priscila Maria Stolses Bergamo Mengue, Sotero Serrate Borges, Rogério Boff Pizzol, Tatiane da Silva Dal Costa, Karen Sarmento Einstein (Sao Paulo) Original Article OBJECTIVE: To estimate the prevalence of use of drugs to treat gastrointestinal disorders, according to demographic, socioeconomic, and health characteristics of the Brazilian population. METHODS: This is a population-based survey that interviewed individuals residing in cities of the five regions in Brazil. The study sample was composed of 32,348 individuals aged 20 or more years. The profile of use of drugs for gastrointestinal disorders was evaluated considering the variables sex, age, healthcare plan, region, and number of chronic diseases. We also analyzed the frequency of individuals who declared using other drugs, besides those already employed for treatment of gastrointestinal disorders. Additionally, the estimated frequencies of the drug classes used were determined. RESULTS: The prevalence of use of drugs for gastrointestinal disorders in Brazil was 6.9% (95% confidence interval − 6.4-7.6), higher in females, among persons aged over 60 years, in those who had a private healthcare insurance, and presented with two or more chronic diseases. It was noted that 42.9% of the aged who used drugs for gastrointestinal disorders were also on polypharmacy. As to the classes of drugs, 82% corresponded to drugs for the food tract and metabolism, particularly proton pumps inhibitors. CONCLUSION: The use of drugs for treatment of gastrointestinal disorders was significant among women and elderly. In this age group, consumption may be linked to gastric protection due to polypharmacy. This study is an unprecedented opportunity to observe the self-reported consumption profile of these drugs in Brazil and, therefore, could subsidize strategies to promote their rational use. Instituto Israelita de Ensino e Pesquisa Albert Einstein 2020-08-06 /pmc/articles/PMC7416649/ /pubmed/32785451 http://dx.doi.org/10.31744/einstein_journal/2020AO5314 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Pereira, Lucas Borges
Gonçalves, Ana Maria Rosa Freato
Fernandes, Camila Stéfani Estancial
Fontanella, Andréia Turmina
Francisco, Priscila Maria Stolses Bergamo
Mengue, Sotero Serrate
Borges, Rogério Boff
Pizzol, Tatiane da Silva Dal
Costa, Karen Sarmento
Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title_full Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title_fullStr Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title_full_unstemmed Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title_short Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines
title_sort use of drugs for gastrointestinal disorders: evidence from national survey on access, use and promotion of rational use of medicines
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416649/
https://www.ncbi.nlm.nih.gov/pubmed/32785451
http://dx.doi.org/10.31744/einstein_journal/2020AO5314
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