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Epigenome‐wide analyses identify DNA methylation signatures of dementia risk
INTRODUCTION: Dementia pathogenesis begins years before clinical symptom onset, necessitating the understanding of premorbid risk mechanisms. Here we investigated potential pathogenic mechanisms by assessing DNA methylation associations with dementia risk factors in Alzheimer's disease (AD)–fre...
Autores principales: | Walker, Rosie M., Bermingham, Mairead L., Vaher, Kadi, Morris, Stewart W., Clarke, Toni‐Kim, Bretherick, Andrew D., Zeng, Yanni, Amador, Carmen, Rawlik, Konrad, Pandya, Kalyani, Hayward, Caroline, Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416667/ https://www.ncbi.nlm.nih.gov/pubmed/32789163 http://dx.doi.org/10.1002/dad2.12078 |
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