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A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia

Schizophrenia is a complex highly heritable disorder. Genome-wide association studies (GWAS) have identified multiple loci that influence the risk of developing schizophrenia, although the causal variants driving these associations and their impacts on specific genes are largely unknown. We identify...

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Detalles Bibliográficos
Autores principales: Hall, Lynsey S, Medway, Christopher W, Pain, Oliver, Pardiñas, Antonio F, Rees, Elliott G, Escott-Price, Valentina, Pocklington, Andrew, Bray, Nicholas J, Holmans, Peter A, Walters, James T R, Owen, Michael J, O’Donovan, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416679/
https://www.ncbi.nlm.nih.gov/pubmed/31691811
http://dx.doi.org/10.1093/hmg/ddz253