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Potential strategies for combating COVID-19

Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approxim...

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Autores principales: Shamim, Saba, Khan, Maryam, Kharaba, Zelal Jaber, Ijaz, Munazza, Murtaza, Ghulam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416802/
https://www.ncbi.nlm.nih.gov/pubmed/32778950
http://dx.doi.org/10.1007/s00705-020-04768-3
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author Shamim, Saba
Khan, Maryam
Kharaba, Zelal Jaber
Ijaz, Munazza
Murtaza, Ghulam
author_facet Shamim, Saba
Khan, Maryam
Kharaba, Zelal Jaber
Ijaz, Munazza
Murtaza, Ghulam
author_sort Shamim, Saba
collection PubMed
description Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure.
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spelling pubmed-74168022020-08-10 Potential strategies for combating COVID-19 Shamim, Saba Khan, Maryam Kharaba, Zelal Jaber Ijaz, Munazza Murtaza, Ghulam Arch Virol Review Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure. Springer Vienna 2020-08-10 2020 /pmc/articles/PMC7416802/ /pubmed/32778950 http://dx.doi.org/10.1007/s00705-020-04768-3 Text en © Springer-Verlag GmbH Austria, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Shamim, Saba
Khan, Maryam
Kharaba, Zelal Jaber
Ijaz, Munazza
Murtaza, Ghulam
Potential strategies for combating COVID-19
title Potential strategies for combating COVID-19
title_full Potential strategies for combating COVID-19
title_fullStr Potential strategies for combating COVID-19
title_full_unstemmed Potential strategies for combating COVID-19
title_short Potential strategies for combating COVID-19
title_sort potential strategies for combating covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416802/
https://www.ncbi.nlm.nih.gov/pubmed/32778950
http://dx.doi.org/10.1007/s00705-020-04768-3
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