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The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems
The application of bioisosteres in drug discovery is a well-established design concept that has demonstrated utility as an approach to solving a range of problems that affect candidate optimization, progression, and durability. In this chapter, the application of isosteric substitution is explored i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416817/ http://dx.doi.org/10.1007/7355_2013_29 |