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Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

Oculogyric crisis is a rare ocular dystonia first appearing at the turn of the last century in postencephalitic patients. In the modern era, they were most frequently associated with first-generation D1 dopaminergic receptor blocking antipsychotic medication. We present an unusual case of acute ocul...

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Autores principales: Wilson, Alphonso, Filatov, Asia, Azhar, Mishah, Swerdloff, Marc, Husain Wilson, Sameea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417033/
https://www.ncbi.nlm.nih.gov/pubmed/32789046
http://dx.doi.org/10.7759/cureus.9100
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author Wilson, Alphonso
Filatov, Asia
Azhar, Mishah
Swerdloff, Marc
Husain Wilson, Sameea
author_facet Wilson, Alphonso
Filatov, Asia
Azhar, Mishah
Swerdloff, Marc
Husain Wilson, Sameea
author_sort Wilson, Alphonso
collection PubMed
description Oculogyric crisis is a rare ocular dystonia first appearing at the turn of the last century in postencephalitic patients. In the modern era, they were most frequently associated with first-generation D1 dopaminergic receptor blocking antipsychotic medication. We present an unusual case of acute oculogyric crisis in a 74-year-old woman with long-standing Parkinson disease following exposure to the second-generation neuroleptic ziprasidone, which has dopaminergic (D2) and serotoninergic (5-HT2A) receptor blocking effects and is used for severe delusions and psychosis. To the best of our knowledge, there are no other published reports.
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spelling pubmed-74170332020-08-11 Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female Wilson, Alphonso Filatov, Asia Azhar, Mishah Swerdloff, Marc Husain Wilson, Sameea Cureus Neurology Oculogyric crisis is a rare ocular dystonia first appearing at the turn of the last century in postencephalitic patients. In the modern era, they were most frequently associated with first-generation D1 dopaminergic receptor blocking antipsychotic medication. We present an unusual case of acute oculogyric crisis in a 74-year-old woman with long-standing Parkinson disease following exposure to the second-generation neuroleptic ziprasidone, which has dopaminergic (D2) and serotoninergic (5-HT2A) receptor blocking effects and is used for severe delusions and psychosis. To the best of our knowledge, there are no other published reports. Cureus 2020-07-09 /pmc/articles/PMC7417033/ /pubmed/32789046 http://dx.doi.org/10.7759/cureus.9100 Text en Copyright © 2020, Wilson et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Wilson, Alphonso
Filatov, Asia
Azhar, Mishah
Swerdloff, Marc
Husain Wilson, Sameea
Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title_full Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title_fullStr Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title_full_unstemmed Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title_short Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female
title_sort ziprasidone-induced oculogyric crisis in a 74-year-old female
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417033/
https://www.ncbi.nlm.nih.gov/pubmed/32789046
http://dx.doi.org/10.7759/cureus.9100
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