Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

The use of cannabis is rapidly expanding worldwide. Thus, innovative studies aimed to identify, understand and potentially reduce cannabis-evoked harms are warranted. Here, we found that Δ(9)-tetrahydrocannabinol, the psychoactive ingredient of cannabis, disrupts autophagy selectively in the striatu...

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Detalles Bibliográficos
Autores principales: Blázquez, Cristina, Ruiz-Calvo, Andrea, Bajo-Grañeras, Raquel, Baufreton, Jérôme M, Resel, Eva, Varilh, Marjorie, Pagano Zottola, Antonio C, Mariani, Yamuna, Cannich, Astrid, Rodríguez-Navarro, José A, Marsicano, Giovanni, Galve-Roperh, Ismael, Bellocchio, Luigi, Guzmán, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417168/
https://www.ncbi.nlm.nih.gov/pubmed/32773031
http://dx.doi.org/10.7554/eLife.56811

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