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Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin cytoskeleton, which are opposed by the cortical cytoskeleton of the interacting antigen-presenting cell. During an immune response, DCs undergo a maturation process that optimizes their ability to efficiently prim...

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Detalles Bibliográficos
Autores principales: Blumenthal, Daniel, Chandra, Vidhi, Avery, Lyndsay, Burkhardt, Janis K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417170/
https://www.ncbi.nlm.nih.gov/pubmed/32720892
http://dx.doi.org/10.7554/eLife.55995