Direct COVID-19 infection of enterocytes: The role of hypochlorhydria

COVD-19 disease is characteristically respiratory in nature; however, some patients have gastrointestinal symptoms. These include changes in taste, nausea/vomiting, abdominal pain, and diarrhea. A report has been published of a young patient who repeatedly tested positive in stool samples while naso...

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Detalles Bibliográficos
Autor principal: Dibner, Julia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417263/
https://www.ncbi.nlm.nih.gov/pubmed/32791258
http://dx.doi.org/10.1016/j.ajic.2020.08.002
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author Dibner, Julia J.
author_facet Dibner, Julia J.
author_sort Dibner, Julia J.
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description COVD-19 disease is characteristically respiratory in nature; however, some patients have gastrointestinal symptoms. These include changes in taste, nausea/vomiting, abdominal pain, and diarrhea. A report has been published of a young patient who repeatedly tested positive in stool samples while nasopharyngeal tests remained negative. This raises doubts about our understanding of the dynamics of COVID-19 disease. The current report describes a need for selective stool testing to explore fecal shedding of viral RNA and presents a hypothesis for direct infection of enterocytes in cases of hypochlorhydria.
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spelling pubmed-74172632020-08-11 Direct COVID-19 infection of enterocytes: The role of hypochlorhydria Dibner, Julia J. Am J Infect Control Brief Report COVD-19 disease is characteristically respiratory in nature; however, some patients have gastrointestinal symptoms. These include changes in taste, nausea/vomiting, abdominal pain, and diarrhea. A report has been published of a young patient who repeatedly tested positive in stool samples while nasopharyngeal tests remained negative. This raises doubts about our understanding of the dynamics of COVID-19 disease. The current report describes a need for selective stool testing to explore fecal shedding of viral RNA and presents a hypothesis for direct infection of enterocytes in cases of hypochlorhydria. Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2021-03 2020-08-11 /pmc/articles/PMC7417263/ /pubmed/32791258 http://dx.doi.org/10.1016/j.ajic.2020.08.002 Text en © 2020 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Dibner, Julia J.
Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title_full Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title_fullStr Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title_full_unstemmed Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title_short Direct COVID-19 infection of enterocytes: The role of hypochlorhydria
title_sort direct covid-19 infection of enterocytes: the role of hypochlorhydria
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417263/
https://www.ncbi.nlm.nih.gov/pubmed/32791258
http://dx.doi.org/10.1016/j.ajic.2020.08.002
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