Acute Lower Limb Ischemia as Clinical Presentation of COVID-19 Infection

Novel 2019 coronavirus (COVID-19) infection usually causes a respiratory disease that may vary in severity from mild symptoms to severe pneumonia with multiple organ failure. Coagulation abnormalities are frequent, and reports suggest that COVID-19 may predispose to venous and arterial thrombotic co...

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Detalles Bibliográficos
Autores principales: Mietto, Cristina, Salice, Valentina, Ferraris, Matteo, Zuccon, Gianmarco, Valdambrini, Federico, Piazzalunga, Giorgio, Socrate, Anna Maria, Radrizzani, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417264/
https://www.ncbi.nlm.nih.gov/pubmed/32791191
http://dx.doi.org/10.1016/j.avsg.2020.08.004
Descripción
Sumario:Novel 2019 coronavirus (COVID-19) infection usually causes a respiratory disease that may vary in severity from mild symptoms to severe pneumonia with multiple organ failure. Coagulation abnormalities are frequent, and reports suggest that COVID-19 may predispose to venous and arterial thrombotic complications. We report a case of acute lower limb ischemia and resistance to heparin as the onset of COVID-19 disease, preceding the development of respiratory failure. This case highlights that the shift of coagulation profile toward hypercoagulability was associated with the acute ischemic event and influenced the therapy.

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