Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects

BACKGROUND: DNA methylation and gene expression are promising biomarkers of various cancers, including non-small cell lung cancer (NSCLC). Besides the main effects of biomarkers, the progression of complex diseases is also influenced by gene-gene (G×G) interactions. RESEARCH QUESTION: Would screenin...

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Detalles Bibliográficos
Autores principales: Zhang, Ruyang, Chen, Chao, Dong, Xuesi, Shen, Sipeng, Lai, Linjing, He, Jieyu, You, Dongfang, Lin, Lijuan, Zhu, Ying, Huang, Hui, Chen, Jiajin, Wei, Liangmin, Chen, Xin, Li, Yi, Guo, Yichen, Duan, Weiwei, Liu, Liya, Su, Li, Shafer, Andrea, Fleischer, Thomas, Moksnes Bjaanæs, Maria, Karlsson, Anna, Planck, Maria, Wang, Rui, Staaf, Johan, Helland, Åslaug, Esteller, Manel, Wei, Yongyue, Chen, Feng, Christiani, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417380/
https://www.ncbi.nlm.nih.gov/pubmed/32113923
http://dx.doi.org/10.1016/j.chest.2020.01.048

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