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Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis

AIM: The present study aimed at investigating the necessity of preoperative liver function tests (LFTs) in patients with uncomplicated gallstone disease before laparoscopic cholecystectomy. BACKGROUND: Significant relationship between common bile duct (CBD) stones and acute cholecystitis is reported...

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Autores principales: Rezaei Tavirani, Majid, Abbasi, Mohammad Amin, Bagaee, Masoud, Tizmaghz, Adnan, Khavanin-Zadeh, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417485/
https://www.ncbi.nlm.nih.gov/pubmed/32821356
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author Rezaei Tavirani, Majid
Abbasi, Mohammad Amin
Bagaee, Masoud
Tizmaghz, Adnan
Khavanin-Zadeh, Morteza
author_facet Rezaei Tavirani, Majid
Abbasi, Mohammad Amin
Bagaee, Masoud
Tizmaghz, Adnan
Khavanin-Zadeh, Morteza
author_sort Rezaei Tavirani, Majid
collection PubMed
description AIM: The present study aimed at investigating the necessity of preoperative liver function tests (LFTs) in patients with uncomplicated gallstone disease before laparoscopic cholecystectomy. BACKGROUND: Significant relationship between common bile duct (CBD) stones and acute cholecystitis is reported. There are contradictory reports about the effect of CBD stones on liver function tests in patients (LFTs). METHODS: In the current study, patients with symptomatic cholelithiasis who referred to hospitals during January 2015 and May 2016 were enrolled. Routine tests and ultrasonography were performed on all patients before surgery. Data were presented as means ± SD and qualitative variables as frequency (percentage) were considered. Statistical analyzes were performed with SPSS software. RESULTS: A consecutive series of 270 patients (58 males and 212 females) who referred for laparoscopic cholecystectomy were enrolled in this retrospective study. Pre- operative LFTs were normal in 249 patients (85%) and abnormal LFT was detected in 41 patients (15 %). CONCLUSION: This study showed that 15 % of patients with cholelithiasis without dilated CBD had impaired LFTs. Routine LFTs in preoperative evaluation of symptomatic cholelithiasis usually reveals normal findings and is not helpful in uncomplicated cholelithiasis.
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spelling pubmed-74174852020-08-19 Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis Rezaei Tavirani, Majid Abbasi, Mohammad Amin Bagaee, Masoud Tizmaghz, Adnan Khavanin-Zadeh, Morteza Gastroenterol Hepatol Bed Bench Original Article AIM: The present study aimed at investigating the necessity of preoperative liver function tests (LFTs) in patients with uncomplicated gallstone disease before laparoscopic cholecystectomy. BACKGROUND: Significant relationship between common bile duct (CBD) stones and acute cholecystitis is reported. There are contradictory reports about the effect of CBD stones on liver function tests in patients (LFTs). METHODS: In the current study, patients with symptomatic cholelithiasis who referred to hospitals during January 2015 and May 2016 were enrolled. Routine tests and ultrasonography were performed on all patients before surgery. Data were presented as means ± SD and qualitative variables as frequency (percentage) were considered. Statistical analyzes were performed with SPSS software. RESULTS: A consecutive series of 270 patients (58 males and 212 females) who referred for laparoscopic cholecystectomy were enrolled in this retrospective study. Pre- operative LFTs were normal in 249 patients (85%) and abnormal LFT was detected in 41 patients (15 %). CONCLUSION: This study showed that 15 % of patients with cholelithiasis without dilated CBD had impaired LFTs. Routine LFTs in preoperative evaluation of symptomatic cholelithiasis usually reveals normal findings and is not helpful in uncomplicated cholelithiasis. Shaheed Beheshti University of Medical Sciences 2020 /pmc/articles/PMC7417485/ /pubmed/32821356 Text en ©2020 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Rezaei Tavirani, Majid
Abbasi, Mohammad Amin
Bagaee, Masoud
Tizmaghz, Adnan
Khavanin-Zadeh, Morteza
Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title_full Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title_fullStr Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title_full_unstemmed Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title_short Evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
title_sort evaluation of preoperative liver function test efficacy in patients with symptomatic cholelithiasis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417485/
https://www.ncbi.nlm.nih.gov/pubmed/32821356
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