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Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda

Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxic...

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Autores principales: Baluku, Joseph Baruch, Anguzu, Godwin, Nassozi, Sylvia, Babirye, Febronius, Namiiro, Sharon, Buyungo, Robert, Sempiira, Mike, Wasswa, Amir, Mulwana, Rose, Ntambi, Samuel, Worodria, William, Andia-Biraro, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417543/
https://www.ncbi.nlm.nih.gov/pubmed/32778729
http://dx.doi.org/10.1038/s41598-020-70472-6
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author Baluku, Joseph Baruch
Anguzu, Godwin
Nassozi, Sylvia
Babirye, Febronius
Namiiro, Sharon
Buyungo, Robert
Sempiira, Mike
Wasswa, Amir
Mulwana, Rose
Ntambi, Samuel
Worodria, William
Andia-Biraro, Irene
author_facet Baluku, Joseph Baruch
Anguzu, Godwin
Nassozi, Sylvia
Babirye, Febronius
Namiiro, Sharon
Buyungo, Robert
Sempiira, Mike
Wasswa, Amir
Mulwana, Rose
Ntambi, Samuel
Worodria, William
Andia-Biraro, Irene
author_sort Baluku, Joseph Baruch
collection PubMed
description Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxication were excluded. We performed HIV testing using immunochromatographic antibody tests (Alere Determine HIV-1/2 and Chembio HIV 1/2 STAT-PAK). TB was confirmed using the Xpert MTB/RIF Ultra assay, performed on single spot sputum samples. We enrolled 272 participants from 42 bars in 5 slums. The prevalence of HIV and TB was 11.4% (95% CI 8.1–15.8) and 15 (95% CI 6–39) per 1,000 population respectively. Predictors of HIV were female sex (aOR 5.87, 95% CI 2.05–16.83), current cigarette smoking (aOR 3.23, 95% CI 1.02–10.26), history of TB treatment (aOR 10.19, 95% CI 3.17–32.82) and CAGE scores of 2–3 (aOR 3.90, 95% CI 1.11–13.70) and 4 (aOR 4.77, 95% CI 1.07–21.35). The prevalence of HIV and TB was twice and four times the national averages respectively. These findings highlight the need for concurrent programmatic screening for both HIV and TB among high risk populations in slums.
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spelling pubmed-74175432020-08-11 Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda Baluku, Joseph Baruch Anguzu, Godwin Nassozi, Sylvia Babirye, Febronius Namiiro, Sharon Buyungo, Robert Sempiira, Mike Wasswa, Amir Mulwana, Rose Ntambi, Samuel Worodria, William Andia-Biraro, Irene Sci Rep Article Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxication were excluded. We performed HIV testing using immunochromatographic antibody tests (Alere Determine HIV-1/2 and Chembio HIV 1/2 STAT-PAK). TB was confirmed using the Xpert MTB/RIF Ultra assay, performed on single spot sputum samples. We enrolled 272 participants from 42 bars in 5 slums. The prevalence of HIV and TB was 11.4% (95% CI 8.1–15.8) and 15 (95% CI 6–39) per 1,000 population respectively. Predictors of HIV were female sex (aOR 5.87, 95% CI 2.05–16.83), current cigarette smoking (aOR 3.23, 95% CI 1.02–10.26), history of TB treatment (aOR 10.19, 95% CI 3.17–32.82) and CAGE scores of 2–3 (aOR 3.90, 95% CI 1.11–13.70) and 4 (aOR 4.77, 95% CI 1.07–21.35). The prevalence of HIV and TB was twice and four times the national averages respectively. These findings highlight the need for concurrent programmatic screening for both HIV and TB among high risk populations in slums. Nature Publishing Group UK 2020-08-10 /pmc/articles/PMC7417543/ /pubmed/32778729 http://dx.doi.org/10.1038/s41598-020-70472-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Baluku, Joseph Baruch
Anguzu, Godwin
Nassozi, Sylvia
Babirye, Febronius
Namiiro, Sharon
Buyungo, Robert
Sempiira, Mike
Wasswa, Amir
Mulwana, Rose
Ntambi, Samuel
Worodria, William
Andia-Biraro, Irene
Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_full Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_fullStr Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_full_unstemmed Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_short Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_sort prevalence of hiv infection and bacteriologically confirmed tuberculosis among individuals found at bars in kampala slums, uganda
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417543/
https://www.ncbi.nlm.nih.gov/pubmed/32778729
http://dx.doi.org/10.1038/s41598-020-70472-6
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