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Cosmc controls B cell homing
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, and the consequent decrease of protein O-glycosylation, induces developmental blocks of mouse B cells. After transfer into wil...
Autores principales: | Zeng, Junwei, Eljalby, Mahmoud, Aryal, Rajindra P., Lehoux, Sylvain, Stavenhagen, Kathrin, Kudelka, Matthew R., Wang, Yingchun, Wang, Jianmei, Ju, Tongzhong, von Andrian, Ulrich H., Cummings, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417590/ https://www.ncbi.nlm.nih.gov/pubmed/32778659 http://dx.doi.org/10.1038/s41467-020-17765-6 |
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