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Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches
Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pathway modeling can become a real nightmare for researchers,...
Autores principales: | Lo-Thong, Ophélie, Charton, Philippe, Cadet, Xavier F., Grondin-Perez, Brigitte, Saavedra, Emma, Damour, Cédric, Cadet, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417601/ https://www.ncbi.nlm.nih.gov/pubmed/32778715 http://dx.doi.org/10.1038/s41598-020-70295-5 |
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