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Calpain‐2 plays a pivotal role in the inhibitory effects of propofol against TNF‐α‐induced autophagy in mouse hippocampal neurons

Calpains are calcium‐dependent proteases and play critical roles in neuronal autophagy induced by inflammation. Propofol has been reported to exert anti‐inflammatory effects in neurons. We aimed to identify whether and how propofol‐modulated calpain activity and neuron autophagy in response to tumou...

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Detalles Bibliográficos
Autores principales: Li, Ying, He, Zhiyong, Lv, Hu, Chen, Wei, Chen, Jiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417688/
https://www.ncbi.nlm.nih.gov/pubmed/32627970
http://dx.doi.org/10.1111/jcmm.15577