Cargando…

Calpain‐2 plays a pivotal role in the inhibitory effects of propofol against TNF‐α‐induced autophagy in mouse hippocampal neurons

Calpains are calcium‐dependent proteases and play critical roles in neuronal autophagy induced by inflammation. Propofol has been reported to exert anti‐inflammatory effects in neurons. We aimed to identify whether and how propofol‐modulated calpain activity and neuron autophagy in response to tumou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ying, He, Zhiyong, Lv, Hu, Chen, Wei, Chen, Jiawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417688/ https://www.ncbi.nlm.nih.gov/pubmed/32627970 http://dx.doi.org/10.1111/jcmm.15577

Ejemplares similares

The effect of propofol on hypoxia‐ and TNF‐α‐mediated BDNF/TrkB pathway dysregulation in primary rat hippocampal neurons
por: Tao, Weiping, et al.
Publicado: (2022)

Propofol protects hippocampal neurons in sleep-deprived rats by inhibiting mitophagy and autophagy
por: Dai, Weixin, et al.
Publicado: (2021)

Inhibitory control of hippocampal inhibitory neurons
por: Chamberland, Simon, et al.
Publicado: (2012)

ER stress and subsequent activated calpain play a pivotal role in skeletal muscle wasting after severe burn injury
por: Ma, Li, et al.
Publicado: (2017)

Neonatal Propofol and Etomidate Exposure Enhance Inhibitory Synaptic Transmission in Hippocampal Cornus Ammonis 1 Pyramidal Neurons
por: Zhang, Jia-Qiang, et al.
Publicado: (2016)

Propofol via Antioxidant Property Attenuated Hypoxia-Mediated Mitochondrial Dynamic Imbalance and Malfunction in Primary Rat Hippocampal Neurons
por: Han, Jingfeng, et al.
Publicado: (2022)

Neuroprotective effect of ketamine against TNF‐α‐induced necroptosis in hippocampal neurons
por: Wang, Lu, et al.
Publicado: (2021)

The Mechanism of TNF-α-Mediated Accumulation of Phosphorylated Tau Protein and Its Modulation by Propofol in Primary Mouse Hippocampal Neurons: Role of Mitophagy, NLRP3, and p62/Keap1/Nrf2 Pathway
por: Zhang, Lin, et al.
Publicado: (2022)

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
por: De Ridder, Kirsten, et al.
Publicado: (2022)

Actin reorganization in hippocampal neurons may play a role in early learning and memory impairment after propofol anesthesia in rats
por: Zhang, Xuena, et al.
Publicado: (2023)

The inhibitory effect of minocycline on radiation-induced neuronal apoptosis via AMPKα1 signaling-mediated autophagy
por: Zhang, Liyuan, et al.
Publicado: (2017)

Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death
por: Wang, Yubin, et al.
Publicado: (2020)

Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells
por: Zhang, Yue, et al.
Publicado: (2019)

Overexpression of phosphoprotein enriched in astrocytes 15 reverses the damage induced by propofol in hippocampal neurons
por: Xian, Feng, et al.
Publicado: (2019)

Necroptosis Mediates TNF-Induced Toxicity of Hippocampal Neurons
por: Liu, Shan, et al.
Publicado: (2014)

Regulatory role of calpain in neuronal death
por: Cheng, Si-ying, et al.
Publicado: (2018)

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons
por: Curcio, M, et al.
Publicado: (2015)

Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX(2)) Mediated TNF-α and IL-6 Production in Macrophages
por: Meng, Tao, et al.
Publicado: (2013)

Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory
por: Nagayoshi, Taikai, et al.
Publicado: (2017)

Calpains in cyanobacteria and the origin of calpains
por: Vešelényiová, Dominika, et al.
Publicado: (2022)

Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease
por: Hazra, Anupam, et al.
Publicado: (2013)

Metabolites of Cerebellar Neurons and Hippocampal Neurons Play Opposite Roles in Pathogenesis of Alzheimer's Disease
por: Du, Jing, et al.
Publicado: (2009)

Membrane potential synchrony of neurons in anterior cingulate cortex plays a pivotal role in generation of neuropathic pain
por: Chen, Zhiyu, et al.
Publicado: (2018)

The role of TNF-α in regulating ketamine-induced hippocampal neurotoxicity
por: Zheng, Xiaozhu, et al.
Publicado: (2015)

Sonic hedgehog promotes autophagy in hippocampal neurons
por: Petralia, Ronald S., et al.
Publicado: (2013)

Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1
por: Ge, Jianyun, et al.
Publicado: (2020)

An Integrative Bioinformatics Analysis of the Potential Mechanisms Involved in Propofol Affecting Hippocampal Neuronal Cells
por: Zhuang, Zhao, et al.
Publicado: (2022)

TNF‐α has both stimulatory and inhibitory effects on mouse monocyte‐derived osteoclastogenesis
por: Cao, Yixuan, et al.
Publicado: (2017)

Activation of neuronal N-methyl-d-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage
por: Chen, Zheng, et al.
Publicado: (2018)

Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons
por: Gerónimo-Olvera, Cristian, et al.
Publicado: (2017)

The protective mechanism of Ginkgolides and Ginkgo flavonoids on the TNF-α induced apoptosis of rat hippocampal neurons and its mechanisms in vitro
por: Guo, Maojuan, et al.
Publicado: (2015)

The propofol-induced mitochondrial damage in fetal rat hippocampal neurons via the AMPK/P53 signaling pathway
por: Xiao, Fei, et al.
Publicado: (2022)

Prokineticin 2 Plays a Pivotal Role in Psoriasis
por: He, Xiaoqin, et al.
Publicado: (2016)

Tissue plasminogen activator (tPA) attenuates propofol-induced apoptosis in developing hippocampal neurons
por: Liang, Chao, et al.
Publicado: (2016)

Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway
por: Chen, Zong, et al.
Publicado: (2022)

Demethylation of HACE1 gene promoter by propofol promotes autophagy of human A549 cells
por: Li, Shanshan, et al.
Publicado: (2020)

Delivery of Topically Applied Calpain Inhibitory Peptide to the Posterior Segment of the Rat Eye
por: Ozaki, Taku, et al.
Publicado: (2015)

Propofol Ameliorates Calpain-induced Collapsin Response Mediator Protein-2 Proteolysis in Traumatic Brain Injury in Rats
por: Yu, Yun, et al.
Publicado: (2015)

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity
por: Menzies, F M, et al.
Publicado: (2015)

α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles
por: Machado, Juliano, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kuekhhlldn8nmatdok55jf1fn4