Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment

The transcriptional repressor Bmi‐1 is involved in cell‐cycle regulation and cell senescence, the deficiency of which has been shown to cause oxidative stress. This study investigated whether Bmi‐1 deficiency plays a role in promoting disc degeneration and the effect of treatment with antioxidant N‐...

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Detalles Bibliográficos
Autores principales: Zhang, Qunhu, Li, Jie, Li, You, Che, Hui, Chen, Ying, Dong, Jianghui, Xian, Cory J., Miao, Dengshun, Wang, Liping, Ren, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417700/
https://www.ncbi.nlm.nih.gov/pubmed/32583517
http://dx.doi.org/10.1111/jcmm.15528

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