Cargando…
WWP2 regulates SIRT1‐STAT3 acetylation and phosphorylation involved in hypertensive angiopathy
WWP2 is a HECT‐type E3 ubiquitin ligase that regulates various physiological and pathological activities by binding to different substrates, but its function and regulatory mechanism in vascular smooth muscle cells (VSMCs) are still unknown. Here, we clarified the role of WWP2 in the regulation of S...
Autores principales: | Zhang, Ying, You, Shilong, Tian, Yichen, Lu, Saien, Cao, Liu, Sun, Yingxian, Zhang, Naijin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417706/ https://www.ncbi.nlm.nih.gov/pubmed/32627301 http://dx.doi.org/10.1111/jcmm.15538 |
Ejemplares similares
-
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation
por: Zhang, Naijin, et al.
Publicado: (2020) -
BAF155 promotes cardiac hypertrophy and fibrosis through inhibition of WWP2-mediated PARP1 ubiquitination
por: Zhang, Naijin, et al.
Publicado: (2023) -
The role of SIRT2 in vascular‐related and heart‐related diseases: A review
por: Wu, Boquan, et al.
Publicado: (2021) -
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia
por: Lu, Xinxin, et al.
Publicado: (2022) -
Deacetylation-dependent regulation of PARP1 by SIRT2 dictates ubiquitination of PARP1 in oxidative stress-induced vascular injury
por: Zhang, Naijin, et al.
Publicado: (2021)