Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)

Iron(III)-promoted rapid three-component deuteration of quinoxalinones with olefins and NaBD(4) is reported for the first time, which provides a novel, economic, and efficient method for the rapid synthesis of deuterated quinoxalinones. In this transformation, a radical pathway is involved according...

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Detalles Bibliográficos
Autores principales: Li, Wanmei, Cai, Heng, Huang, Lin, He, Lei, Zhang, Yilan, Xu, Jun, Zhang, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417774/
https://www.ncbi.nlm.nih.gov/pubmed/32850638
http://dx.doi.org/10.3389/fchem.2020.00606
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author Li, Wanmei
Cai, Heng
Huang, Lin
He, Lei
Zhang, Yilan
Xu, Jun
Zhang, Pengfei
author_facet Li, Wanmei
Cai, Heng
Huang, Lin
He, Lei
Zhang, Yilan
Xu, Jun
Zhang, Pengfei
author_sort Li, Wanmei
collection PubMed
description Iron(III)-promoted rapid three-component deuteration of quinoxalinones with olefins and NaBD(4) is reported for the first time, which provides a novel, economic, and efficient method for the rapid synthesis of deuterated quinoxalinones. In this transformation, a radical pathway is involved according to the results of control experiments.
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spelling pubmed-74177742020-08-25 Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4) Li, Wanmei Cai, Heng Huang, Lin He, Lei Zhang, Yilan Xu, Jun Zhang, Pengfei Front Chem Chemistry Iron(III)-promoted rapid three-component deuteration of quinoxalinones with olefins and NaBD(4) is reported for the first time, which provides a novel, economic, and efficient method for the rapid synthesis of deuterated quinoxalinones. In this transformation, a radical pathway is involved according to the results of control experiments. Frontiers Media S.A. 2020-08-04 /pmc/articles/PMC7417774/ /pubmed/32850638 http://dx.doi.org/10.3389/fchem.2020.00606 Text en Copyright © 2020 Li, Cai, Huang, He, Zhang, Xu and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Li, Wanmei
Cai, Heng
Huang, Lin
He, Lei
Zhang, Yilan
Xu, Jun
Zhang, Pengfei
Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title_full Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title_fullStr Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title_full_unstemmed Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title_short Iron(III)-Mediated Rapid Radical-Type Three-Component Deuteration of Quinoxalinones With Olefins and NaBD(4)
title_sort iron(iii)-mediated rapid radical-type three-component deuteration of quinoxalinones with olefins and nabd(4)
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417774/
https://www.ncbi.nlm.nih.gov/pubmed/32850638
http://dx.doi.org/10.3389/fchem.2020.00606
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