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Interleukin 12-containing influenza virus-like-particle vaccine elevate its protective activity against heterotypic influenza virus infection

To produce monovalent and bivalent influenza vaccines composed of virus-like particles (VLPs) containing hemagglutinin (HA), we generated four recombinant Baculoviruses derived from Bombyx mori nuclear polyhedrosis virus (BmNPV) and Autographa california nuclear polyhedrosis virus (AcNPV). Monovalen...

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Detalles Bibliográficos
Autores principales: Maegawa, Kenichi, Sugita, Shigeo, Arasaki, Youta, Nerome, Reiko, Nerome, Kuniaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417893/
https://www.ncbi.nlm.nih.gov/pubmed/32802975
http://dx.doi.org/10.1016/j.heliyon.2020.e04543