Cargando…

CYP2D6 Genotype-Based Dose Recommendations for Risperidone in Asian People

The aim of this study was to provide dose recommendations for risperidone in Asian people based on cytochrome P450 enzyme CYP2D6 genotype. First, we investigated the influence of CYP2D6 polymorphism on the pharmacokinetics of risperidone in Chinese patients with schizophrenia. Then, we performed a s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yuanxia, Yan, Hao, Su, Yi, Wang, Lifang, Lu, Tianlan, Zhang, Dai, Yue, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417932/ https://www.ncbi.nlm.nih.gov/pubmed/32848719 http://dx.doi.org/10.3389/fphar.2020.00936

Ejemplares similares

CYP2D6 genotype and adverse events to risperidone in children and adolescents
por: Oshikoya, Kazeem A., et al.
Publicado: (2019)

CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry
por: Molden, Espen, et al.
Publicado: (2021)

CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6(*)15 and (*)35 Genotyping
por: Riffel, Amanda K., et al.
Publicado: (2016)

C677T Polymorphism in the MTHFR Gene Is Associated With Risperidone-Induced Weight Gain in Schizophrenia
por: Liao, Jingping, et al.
Publicado: (2020)

CYP2D6 polymorphisms and their influence on risperidone treatment
por: Puangpetch, Apichaya, et al.
Publicado: (2016)

Age, Weight, and CYP2D6 Genotype Are Major Determinants of Primaquine Pharmacokinetics in African Children
por: Gonçalves, Bronner P., et al.
Publicado: (2017)

Improved Prediction of Endoxifen Metabolism by CYP2D6 Genotype in Breast Cancer Patients Treated with Tamoxifen
por: Schroth, Werner, et al.
Publicado: (2017)

Relationship between CYP2D6 genotype, activity score and phenotype in a pediatric Thai population treated with risperidone
por: Hongkaew, Yaowaluck, et al.
Publicado: (2021)

Impact of the CYP2D6 Genotype on Metoprolol Tolerance and Adverse Events in Elderly Chinese Patients With Cardiovascular Diseases
por: Chen, Jianqiao, et al.
Publicado: (2022)

The Identification of Novel CYP2D6 Variants in US Hmong: Results From Genome Sequencing and Clinical Genotyping
por: Wen, Ya Feng, et al.
Publicado: (2022)

The impact of CYP2C19 genotype on phenoconversion by concomitant medication
por: de Jong, Laura M., et al.
Publicado: (2023)

Differential Impact of Nevirapine on Artemether-Lumefantrine Pharmacokinetics in Individuals Stratified by CYP2B6 c.516G>T Genotypes
por: Abdullahi, Sa’ad T., et al.
Publicado: (2020)

Methylome-wide association study of different responses to risperidone in schizophrenia
por: Du, Huihui, et al.
Publicado: (2022)

Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug
por: Li, Qian, et al.
Publicado: (2021)

Practice of CYP450 genotyping and phenotyping in children in a real-life setting
por: Rodieux, Frédérique, et al.
Publicado: (2023)

Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone
por: Lu, Jinjun, et al.
Publicado: (2021)

Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy
por: Bérard, Anick, et al.
Publicado: (2017)

Impact of CYP2D6 genotype on opioid use disorder deprescription: an observational prospective study in chronic pain with sex-differences
por: Muriel, Javier, et al.
Publicado: (2023)

Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film
por: Chen, Fang, et al.
Publicado: (2020)

Replication of Association between Schizophrenia and Chromosome 6p21-6p22.1 Polymorphisms in Chinese Han Population
por: Zhang, Yang, et al.
Publicado: (2013)

CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting
por: Ing Lorenzini, Kuntheavy, et al.
Publicado: (2021)

The impact of CYP2D6*41 on CYP2D6 enzyme activity using phenotyping methods in urine, plasma, and saliva
por: Jin, Ye, et al.
Publicado: (2022)

The pharmacogenetics of CYP2D6 and CYP2C19 in a case series of antidepressant responses
por: Kee, Ping Siu, et al.
Publicado: (2023)

CYP2J2(∗)7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients
por: Ahmed, Jemal Hussien, et al.
Publicado: (2019)

External Evaluation of Risperidone Population Pharmacokinetic Models Using Opportunistic Pediatric Data
por: Karatza, Eleni, et al.
Publicado: (2022)

Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone
por: Soria-Chacartegui, Paula, et al.
Publicado: (2021)

Genetic variation in the 3′-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance
por: Swart, Marelize, et al.
Publicado: (2014)

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2
por: Wang, Xing-he, et al.
Publicado: (2017)

Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G→T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis
por: Nightingale, Sam, et al.
Publicado: (2016)

Understanding inter-individual variability in pharmacokinetics/pharmacodynamics of aripiprazole in children with tic disorders: Individualized administration based on physiological development and CYP2D6 genotypes
por: Xin, Yingying, et al.
Publicado: (2022)

CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients
por: Yang, Yilei, et al.
Publicado: (2021)

A frequent CYP2D6 variant promotes skipping of exon 3 and reduces CYP2D6 protein expression in human liver samples
por: Collins, Joseph M., et al.
Publicado: (2023)

Characterization of complex structural variation in the CYP2D6-CYP2D7-CYP2D8 gene loci using single-molecule long-read sequencing
por: Turner, Amy J., et al.
Publicado: (2023)

A systematic review of the effects of CYP2D6 phenotypes on risperidone treatment in children and adolescents
por: Dodsworth, Thomas, et al.
Publicado: (2018)

Identification and Analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in Cynomolgus Macaques
por: UNO, Yasuhiro, et al.
Publicado: (2014)

Risperidone-Induced Obesity in Children and Adolescents With Autism Spectrum Disorder: Genetic and Clinical Risk Factors
por: Vanwong, Natchaya, et al.
Publicado: (2020)

CYP2D6 Phenotyping Using Urine, Plasma, and Saliva Metabolic Ratios to Assess the Impact of CYP2D6(∗)10 on Interindividual Variation in a Chinese Population
por: Chen, Rui, et al.
Publicado: (2017)

MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?
por: de la Torre, Rafael, et al.
Publicado: (2012)

Hyperuricemia in Children and Adolescents with Autism Spectrum Disorder Treated with Risperidone: The Risk Factors for Metabolic Adverse Effects
por: Vanwong, Natchaya, et al.
Publicado: (2017)

Pharmacogenomics Factors Influencing the Effect of Risperidone on Prolactin Levels in Thai Pediatric Patients With Autism Spectrum Disorder
por: Hongkaew, Yaowaluck, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1fdli4v0ugfitf2n47s4g851d4