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KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism

To define the regulatory role of Kruppel-like factor 2 (KLF2) during osteoblast (OB) differentiation of dental pulp-derived stem cell (DPSC)s, herein, we show that the levels of KLF2 and autophagy-related molecules were significantly increased in differentiated cells. Gain-of-function and loss-of-fu...

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Detalles Bibliográficos
Autores principales: Maity, Jyotirindra, Deb, Moonmoon, Greene, Carl, Das, Hiranmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417940/
https://www.ncbi.nlm.nih.gov/pubmed/32777717
http://dx.doi.org/10.1016/j.redox.2020.101622