Chemo- and Diastereoselective Hydrosilylation of Amorphadiene toward the Synthesis of Artemisinin

[Image: see text] A formal synthesis of artemisinin starting from amorphadiene is described. This new route relies on the development of a catalytic chemo- and diastereoselective hydrosilylation. The practicability of this method is demonstrated by converting amorphadiene to dihydroartemisinic aldeh...

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Detalles Bibliográficos
Autores principales: Schwertz, Geoffrey, Zanetti, Andrea, de Oliveira, Marllon Nascimento, Fernandez, Mario Andrés Gomez, Amara, Zacharias, Cossy, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418106/
https://www.ncbi.nlm.nih.gov/pubmed/32643937
http://dx.doi.org/10.1021/acs.joc.0c00617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418106/
https://www.ncbi.nlm.nih.gov/pubmed/32643937
http://dx.doi.org/10.1021/acs.joc.0c00617

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